Skip to main content
PKC phosphorylates HEXIM1 and regulates P-TEFb activity
- Author(s): Peterlin, Boris
- Fujinaga, K
- Barboric, M
- Li, Q
- Luo, Z
- Price, DH
- Peterlin, BM
- et al.
Published Web Location
http://europepmc.org/articles/PMC3467075?pdf=renderNo data is associated with this publication.
Abstract
The positive transcription elongation factor b (P-TEFb) regulates RNA polymerase II elongation. In cells, P-TEFb partitions between small active and larger inactive states. In the latter, HEXIM1 binds to 7SK snRNA and recruits as well as inactivates P-TEFb
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.