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Single-cell DNA sequencing reveals complex mechanisms of resistance to quizartinib
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https://doi.org/10.1182/bloodadvances.2020003398Abstract
Single-cell sequencing exposes previously unmeasurable complexity of tumor heterogeneity and clonal evolution on quizartinib. Single-cell sequencing reveals on- and off-target mechanisms of resistance to quizartinib, which can preexist therapy.
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