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Sequential primed kinases create a damage-responsive phosphodegron on Eco1
Published Web Location
http://europepmc.org/articles/PMC3565030?pdf=renderNo data is associated with this publication.
Abstract
Sister-chromatid cohesion is established during S phase when Eco1 acetylates cohesin. In budding yeast, Eco1 activity falls after S phase due to Cdk1-dependent phosphorylation, which triggers ubiquitination by SCF Cdc4. We show here that Eco1 degradation r
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