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Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

et al.

Published Web Location

https://doi.org/10.1007/s10577-013-9347-y
Creative Commons 'BY-NC' version 4.0 license
Abstract

The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres.

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