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A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2

Published Web Location

http://europepmc.org/articles/PMC4128814?pdf=render
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Abstract

Lipoxygenase (LOX) enzymes catalyze the hydroperoxidation of arachidonic acid and other polyunsaturated fatty acids to hydroxyeicosatetraenoic acids with varying positional specificity to yield important biological signaling molecules. Human epithelial 15-

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