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Can ovarian suppression with gonadotropin-releasing hormone analogs (GnRHa) preserve fertility in cancer patients?
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https://doi.org/10.1093/annonc/mdv554Abstract
Ovarian suppression via Gonadotropin releasing hormone analog (GnRHa) treatment should remain as an unproven method of fertility preservation due to lack of biological plausibility, conflicting results, and design flaws in the studies which include the lack of placebo and blinding and the utility of improper surrogates for fertility and ovarian reserve.
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