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Global Gene Regulation in Desulfovibrio vulgaris Hildenborough

  • Author(s): Zhou, Aifen
  • He, Zhili
  • Hemme, Chris
  • Mukhopadhyay, Aindrila
  • Keasling, Jay
  • Arkin, Adam P.
  • Hazen, Terry C.
  • Wall, Judy D.
  • Zhou, Jizhong
  • et al.
Abstract

Desulfovibrio vulgaris Hildenborough (DvH) is an obligate anaerobe and has been used as a model organism for studying the energy metabolism of sulfate-reducing bacterium (SRB). However, experimental data about the transcriptional regulatory networks which are essential for understanding the cellular processes are very limited. In this study, several predicted global regulators are investigated via mutant characterization, transcriptomic assay and their in vivo gene regulations using ChIP-chip assay.

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