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Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum

  • Author(s): Moasser, Mark
  • Ruiz-Saenz, A
  • Sandhu, M
  • Carrasco, Y
  • Maglathlin, RL
  • Taunton, J
  • Moasser, MM
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4515412?pdf=render
No data is associated with this publication.
Abstract

© 2015 Macmillan Publishers Limited There is increasing evidence implicating human epidermal growth factor receptor 3 (HER3) in several types of cancer. However, the development of targeted therapies to inactivate HER3 function has been a challenging endea

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