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Despite intense study, much is still unknown about mosquito-borne diseases. Many unanswered questions remain about these four diseases associated with Ae. aegypti and Ae. albopictus: chikungunya, dengue, yellow fever, and Zika, while the threat of their outbreaks and expansion continues to increase. A major gap in our knowledge of these diseases is in the factors that are associated with human cases of infection. As our understanding of the relationship between factors (environmental and socioeconomic) and cases of mosquito-borne disease increases, methods of preventing outbreaks can improve.
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