Load Regulates Bone Formation and Sclerostin Expression through a TGFβ-Dependent Mechanism
- Author(s): Alliston, Tamara
- Nguyen, J
- Tang, SY
- Nguyen, D
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3538690?pdf=render
Bone continually adapts to meet changing physical and biological demands. Osteoblasts, osteoclasts, and osteocytes cooperate to integrate these physical and biochemical cues to maintain bone homeostasis. Although TGFβ acts on all three of these cell types