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ENU-induced Mutation in the DNA-binding Domain of KLF3 Reveals Important Roles for KLF3 in Cardiovascular Development and Function in Mice

  • Author(s): Bruneau, Benoit
  • Kelsey, L
  • Flenniken, AM
  • Qu, D
  • Funnell, APW
  • Pearson, R
  • Zhou, YQ
  • Voronina, I
  • Berberovic, Z
  • Wood, G
  • Newbigging, S
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3708807?pdf=render
No data is associated with this publication.
Abstract

KLF3 is a Krüppel family zinc finger transcription factor with widespread tissue expression and no previously known role in heart development. In a screen for dominant mutations affecting cardiovascular function in N-ethyl-N-nitrosourea (ENU) mutagenized m

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