Skip to main content
eScholarship
Open Access Publications from the University of California

Volumetric microvascular imaging of human retina using optical coherence tomography with a novel motion contrast technique

  • Author(s): Fingler, J
  • Zawadzki, RJ
  • Werner, JS
  • Schwartz, D
  • Fraserl, SE
  • et al.
Abstract

Phase variance-based motion contrast imaging is demonstrated using a spectral domain optical coherence tomography system for the in vivo human retina. This contrast technique spatially identifies locations of motion within the retina primarily associated with vasculature. Histogrambased noise analysis of the motion contrast images was used to reduce the motion noise created by transverse eye motion. En face summation images created from the 3D motion contrast data are presented with segmentation of selected retinal layers to provide non-invasive vascular visualization comparable to currently used invasive angiographic imaging. This motion contrast technique has demonstrated the ability to visualize resolutionlimited vasculature independent of vessel orientation and flow velocity. © 2009 Optical Society of America.

Many UC-authored scholarly publications are freely available on this site because of the UC Academic Senate's Open Access Policy. Let us know how this access is important for you.

Main Content
Current View