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Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen

  • Author(s): Greene, Warner
  • Usmani, SM
  • Zirafi, O
  • Müller, JA
  • Sandi-Monroy, NL
  • Yadav, JK
  • Meier, C
  • Weil, T
  • Roan, NR
  • Greene, WC
  • Walther, P
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4129123?pdf=render
No data is associated with this publication.
Abstract

Naturally occurring fragments of the abundant semen proteins prostatic acid phosphatase (PAP) and semenogelins form amyloid fibrils in vitro. These fibrils boost HIV infection and may play a key role in the spread of the AIDS pandemic. However, the presenc

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