- Main
The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB‐fold
- Das, Debanu;
- Kozbial, Piotr;
- Han, Gye Won;
- Carlton, Dennis;
- Jaroszewski, Lukasz;
- Abdubek, Polat;
- Astakhova, Tamara;
- Axelrod, Herbert L;
- Bakolitsa, Constantina;
- Chen, Connie;
- Chiu, Hsiu-Ju;
- Chiu, Michelle;
- Clayton, Thomas;
- Deller, Marc C;
- Duan, Lian;
- Ellrott, Kyle;
- Elsliger, Marc-André;
- Ernst, Dustin;
- Farr, Carol L;
- Feuerhelm, Julie;
- Grzechnik, Anna;
- Grant, Joanna C;
- Jin, Kevin K;
- Johnson, Hope A;
- Klock, Heath E;
- Knuth, Mark W;
- Krishna, S Sri;
- Kumar, Abhinav;
- Marciano, David;
- McMullan, Daniel;
- Miller, Mitchell D;
- Morse, Andrew T;
- Nigoghossian, Edward;
- Nopakun, Amanda;
- Okach, Linda;
- Oommachen, Silvya;
- Paulsen, Jessica;
- Puckett, Christina;
- Reyes, Ron;
- Rife, Christopher L;
- Sefcovic, Natasha;
- Tien, Henry J;
- Trame, Christine B;
- van den Bedem, Henry;
- Weekes, Dana;
- Wooten, Tiffany;
- Xu, Qingping;
- Hodgson, Keith O;
- Wooley, John;
- Deacon, Ashley M;
- Godzik, Adam;
- Lesley, Scott A;
- Wilson, Ian A
- et al.
Published Web Location
https://doi.org/10.1107/s1744309109018168Abstract
KPN03535 (gi|152972051) is a putative lipoprotein of unknown function that is secreted by Klebsiella pneumoniae MGH 78578. The crystal structure reveals that despite a lack of any detectable sequence similarity to known structures, it is a novel variant of the OB-fold and structurally similar to the bacterial Cpx-pathway protein NlpE, single-stranded DNA-binding (SSB) proteins and toxins. K. pneumoniae MGH 78578 forms part of the normal human skin, mouth and gut flora and is an opportunistic pathogen that is linked to about 8% of all hospital-acquired infections in the USA. This structure provides the foundation for further investigations into this divergent member of the OB-fold family.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.
Main Content
Enter the password to open this PDF file:
-
-
-
-
-
-
-
-
-
-
-
-
-
-