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Open Access Publications from the University of California

Automatic three-dimensional segmentation combined with in vivo microvascular network imaging of human retina by intensity-based Doppler variance optical coherence tomography

  • Author(s): Piao, Z
  • Huang, S
  • Qi, L
  • Zhu, J
  • Lu, F
  • Chen, Z
  • et al.

Copyright © 2016 SPIE. Optical coherence tomography (OCT) is a noninvasive method for retinal imaging. In this work, we present an in vivo human retinal microvascular network measurement by an intensity-based Doppler variance (IBDV) based on sweptsource OCT. In addition, an automatic three-dimensional (3-D) segmentation method was used for segmenting intraretinal layers. The microvascular networks were divided into six layers by visualizing of each individual layer with enhanced imaging contrast. This method has potential for earlier diagnosis and precise monitoring in retinal vascular diseases.

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