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Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity

Published Web Location

http://europepmc.org/articles/PMC3354320?pdf=render
No data is associated with this publication.
Abstract

Rapamycin, a specific inhibitor for mTOR complex 1, is an FDA-approved immunosuppressant for organ transplant. Recent developments have raised the prospect of using rapamycin to treat cancer or diabetes and to delay aging. It is therefore important to asse

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