Left ventricular pressure gating in ovine cardiac studies: a software-based method.
- Author(s): Acevedo-Bolton, Gabriel;
- Suzuki, Takamaro;
- Malhotra, Deepak;
- Zhang, Zhihong;
- Wallace, Arthur W;
- Guccione, Julius M;
- Saloner, David A;
- Ratcliffe, Mark B
- et al.
Published Web Locationhttps://doi.org/10.1115/1.4023370
Cardiac imaging using magnetic resonance requires a gating signal in order to compensate for motion. Human patients are routinely scanned using an electrocardiogram (ECG) as a gating signal during imaging. However, we found that in sheep the ECG is not a reliable method for gating. We developed a software based method that allowed us to use the left ventricular pressure (LVP) as a reliable gating signal. By taking the time derivative of the LVP (dP/dt), we were able to start imaging at both end-diastole for systolic phase images, and end-systole for diastolic phase images. We also used MR tissue tagging to calculate 3D strain information during diastole. Using the LVP in combination with our digital circuit provided a reliable and time efficient method for ovine cardiac imaging. Unlike the ECG signal the left ventricular pressure was a clean signal and allowed for accurate, nondelay based triggering during systole and diastole.