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Open Access Publications from the University of California

Left ventricular pressure gating in ovine cardiac studies: a software-based method.

  • Author(s): Acevedo-Bolton, Gabriel
  • Suzuki, Takamaro
  • Malhotra, Deepak
  • Zhang, Zhihong
  • Wallace, Arthur W
  • Guccione, Julius M
  • Saloner, David A
  • Ratcliffe, Mark B
  • et al.

Published Web Location

Cardiac imaging using magnetic resonance requires a gating signal in order to compensate for motion. Human patients are routinely scanned using an electrocardiogram (ECG) as a gating signal during imaging. However, we found that in sheep the ECG is not a reliable method for gating. We developed a software based method that allowed us to use the left ventricular pressure (LVP) as a reliable gating signal. By taking the time derivative of the LVP (dP/dt), we were able to start imaging at both end-diastole for systolic phase images, and end-systole for diastolic phase images. We also used MR tissue tagging to calculate 3D strain information during diastole. Using the LVP in combination with our digital circuit provided a reliable and time efficient method for ovine cardiac imaging. Unlike the ECG signal the left ventricular pressure was a clean signal and allowed for accurate, nondelay based triggering during systole and diastole.

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