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Epidermal or dermal specific knockout of PHD-2 enhances wound healing and minimizes ischemic injury

  • Author(s): Chan, Denise
  • Zimmermann, AS
  • Morrison, SD
  • Hu, MS
  • Li, S
  • Nauta, A
  • Sorkin, M
  • Meyer, NP
  • Walmsley, GG
  • Maan, ZN
  • Chan, DA
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3973687?pdf=render
No data is associated with this publication.
Abstract

Introduction: Hypoxia-inducible factor (HIF)-1α, part of the heterodimeric transcription factor that mediates the cellular response to hypoxia, is critical for the expression of multiple angiogenic growth factors, cell motility, and the recruitment of endo

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