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Direct and indirect targets of the E2A-PBX1 leukemia-specific fusion protein

  • Author(s): Wiemels, Joseph
  • Diakos, C
  • Xiao, Y
  • Zheng, S
  • Kager, L
  • Dworzak, M
  • Wiemels, JL
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3913655?pdf=render
No data is associated with this publication.
Abstract

E2A-PBX1 is expressed as a result of the t(1;19) chromosomal translocation in nearly 5% of cases of childhood acute lymphoblastic leukemia. The E2A-PBX1 chimeric transcription factor contains the N-terminal transactivation domain of E2A (TCF3) fused to the

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