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In vitro membrane reconstitution of the T-cell receptor proximal signaling network

  • Author(s): Vale, Ronald
  • Hui, E
  • Vale, RD
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4062301?pdf=render
No data is associated with this publication.
Abstract

T-cell receptor (TCR) phosphorylation is controlled by a complex network that includes Lck, a Src family kinase (SFK), the tyrosine phosphatase CD45 and the Lck-inhibitory kinase Csk. How these competing phosphorylation and dephosphorylation reactions are

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