Skip to main content
eScholarship
Open Access Publications from the University of California

Dermatology Online Journal

Dermatology Online Journal bannerUC Davis

Fish odor syndrome: a case report of trimethylaminuria

  • Author(s): Ulman, Catherine A;
  • Trevino, Julian J;
  • Miller, Marvin;
  • Gandhi, Rishi K
  • et al.
Abstract

Trimethylaminuria is a rare, autosomal recessive, metabolic disorder that results in accumulation of trimethylamine (TMA), which smells like rotten fish. The chemical is excreted in sweat and urine owing to a deficiency in the enzyme flavin monooxygenase 3 (FMO3). We report a case of trimethylaminuria in a 12-year-old girl. The patient failed treatment with diet and hygiene modification, but achieved symptomatic improvement after a four-month course of metronidazole.

Main Content
For improved accessibility of PDF content, download the file to your device.
Current View