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Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance

Published Web Location

http://europepmc.org/articles/PMC4010907?pdf=render
No data is associated with this publication.
Abstract

Thymic central tolerance is a critical process that prevents autoimmunity but also presents a challenge to the generation of anti-tumor immune responses. Medullary thymic epithelial cells (mTECs) eliminate self-reactive T cells by displaying a diverse repe

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