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Autistic-like behaviour in Scn1a +- mice and rescue by enhanced GABA-mediated neurotransmission

Published Web Location

http://europepmc.org/articles/PMC3448848?pdf=render
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Abstract

Haploinsufficiency of the SCN1A gene encoding voltage-gated sodium channel Na V 1.1 causes Dravets syndrome, a childhood neuropsychiatric disorder including recurrent intractable seizures, cognitive deficit and autism-spectrum behaviours. The neural mechan

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