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Open Access Publications from the University of California

Autistic-like behaviour in Scn1a +- mice and rescue by enhanced GABA-mediated neurotransmission

  • Author(s): Rubenstein, John
  • Han, S
  • Tai, C
  • Westenbroek, RE
  • Yu, FH
  • Cheah, CS
  • Potter, GB
  • Rubenstein, JL
  • Scheuer, T
  • De, HO
  • Catterall, WA
  • et al.

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Haploinsufficiency of the SCN1A gene encoding voltage-gated sodium channel Na V 1.1 causes Dravets syndrome, a childhood neuropsychiatric disorder including recurrent intractable seizures, cognitive deficit and autism-spectrum behaviours. The neural mechan

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