UC Irvine

Although adverse effects of radiographic contrast medium, ranging from minor rashes to anaphylactic reactions, are not rare during various radiologic procedures, thrombocytopenia has been extremely rare, and only a few cases of acute severe thrombocytopenia have been described [1 -8]. In five reported patients, thrombocytopenia developed after oral administration of radiographic contrast material [1 -4, 6], and in four patients it followed IV injection [5, 7, 8]. In this report, another case of acute severe thrombocytopenia due to an IV contrast medium is described.