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Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development

Published Web Location

http://europepmc.org/articles/PMC4095875?pdf=render
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Abstract

The catalytic activity of Zap70 is crucial for T cell antigen receptor (TCR) signaling, but the quantitative and temporal requirements for its function in thymocyte development are not known. Using a chemical-genetic system to selectively and reversibly in

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