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Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development
Published Web Location
http://europepmc.org/articles/PMC4095875?pdf=renderNo data is associated with this publication.
Abstract
The catalytic activity of Zap70 is crucial for T cell antigen receptor (TCR) signaling, but the quantitative and temporal requirements for its function in thymocyte development are not known. Using a chemical-genetic system to selectively and reversibly in
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