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Enteric defensins are essential regulators of intestinal microbial ecology
- Salzman, Nita H;
- Hung, Kuiechun;
- Haribhai, Dipica;
- Chu, Hiutung;
- Karlsson-Sjöberg, Jenny;
- Amir, Elad;
- Teggatz, Paul;
- Barman, Melissa;
- Hayward, Michael;
- Eastwood, Daniel;
- Stoel, Maaike;
- Zhou, Yanjiao;
- Sodergren, Erica;
- Weinstock, George M;
- Bevins, Charles L;
- Williams, Calvin B;
- Bos, Nicolaas A
Published Web Location
https://doi.org/10.1038/ni.1825Abstract
Defensins combat pathogenic bacteria invading the mammalian intestine. Salzman and co-workers find that defensins influence the composition of the small intestinal commensal microbiota and the presence of interleukin 17–producing T cells in the lamina propria.
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