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Endocrine–exocrine signals in obesity-associated pancreatic cancer
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https://doi.org/10.1038/s41575-020-0324-6Abstract
Obesity is a known risk factor for pancreatic cancer. Now, a new study reports that obesity accelerates early pancreatic cancer development and growth in mice through local perturbations in the pancreatic microenvironment and implicates pancreatic islet-derived cholecystokinin as a driving factor.
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