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Chasing One-Carbon Units to Understand the Role of Serine in Epigenetics
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https://doi.org/10.1016/j.molcel.2016.01.006Abstract
In this issue of Molecular Cell, Maddocks et al. (2016) use stable isotope tracing, mass spectrometry, and nutrient modulation in cancer cells to highlight the role of serine in supporting methylation through maintenance of nucleotide levels.
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