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Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry

Published Web Location

http://europepmc.org/articles/PMC3688991?pdf=render
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Abstract

Fixed, paraffin-embedded (FPE) tissues are a potentially rich resource for studying the role of NOTCH1 in cancer and other pathologies, but tests that reliably detect activated NOTCH1 (NICD1) in FPE samples have been lacking. Here, we bridge this gap by de

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