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Open Access Publications from the University of California

Effectiveness of intervention on improvement of drug use among methadone maintained adults.

  • Author(s): Nyamathi, Adeline M
  • Nandy, Karabi
  • Greengold, Barbara
  • Marfisee, Mary
  • Khalilifard, Farinaz
  • Cohen, Allan
  • Leake, Barbara
  • et al.

The purpose of this study is to evaluate the effectiveness of three interventions (individual motivational interviewing, group motivational interviewing, or nurse-led hepatitis health promotion) in reducing drug use. A randomized, controlled trial was conducted with 256 methadone maintained moderate-to-heavy alcohol-using adults attending one of five MM outpatient clinics. Drug use in the overall sample was significantly reduced from baseline to 6-month follow-up, as assessed by a 30-day recall (p < 0.0001), with a trend apparent for 6-month recall (p = 0.09). The group and individual programs revealed significant decreases in drug use at the 30-day recall.

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