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Metabolic and thermal stimuli control K 2P 2.1 (TREK-1) through modular sensory and gating domains

  • Author(s): Minor, Daniel
  • Bagriantsev, SN
  • Clark, KA
  • Minor, DL
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3411076?pdf=render
No data is associated with this publication.
Abstract

K 2P 2.1 (TREK-1) is a polymodal two-pore domain leak potassium channel that responds to external pH, GPCR-mediated phosphorylation signals, and temperature through the action of distinct sensors within the channel. How the various intracellular and extrac

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