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Chronic Traumatic Encephalopathy Presenting as Alzheimer's Disease in a Retired Soccer Player

  • Author(s): Grinberg, LT
  • Anghinah, R
  • Nascimento, CF
  • Jr, AE
  • Leite, RP
  • Martin, MDGM
  • Naslavsky, MS
  • Takada, LT
  • Jacob Filho, W
  • Pasqualucci, CA
  • Nitrini, R
  • et al.
Abstract

The relationship between soccer and chronic traumatic encephalopathy (CTE) is not well established. We report clinicopathological correlations in an 83-year-old retired center-back soccer player, with no history of concussion, manifesting typical Alzheimer-type dementia. Examination revealed mixed pathology including widespread CTE, moderate Alzheimer's disease, hippocampal sclerosis, and TDP-43 proteinopathy. This case adds to a few CTE cases described in soccer players. Furthermore, it corroborates that CTE may present clinically as typical Alzheimer-type dementia. Further studies investigating the extent to which soccer is a risk for CTE are needed.

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