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Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies.

  • Author(s): Russel, Daniel;
  • Lasker, Keren;
  • Webb, Ben;
  • Velázquez-Muriel, Javier;
  • Tjioe, Elina;
  • Schneidman-Duhovny, Dina;
  • Peterson, Bret;
  • Sali, Andrej
  • et al.

A set of software tools for building and distributing models of macromolecular assemblies uses an integrative structure modeling approach, which casts the building of models as a computational optimization problem where information is encoded into a scoring function used to evaluate candidate models.

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