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Prolonged and Substantial Discordance in Prevalence of Raltegravir-Resistant HIV-1 in Plasma versus PBMC Samples Revealed by 454 "Deep" Sequencing

  • Author(s): Deeks, Steven
  • Martin, Jeffrey
  • Lee, GQ
  • Swenson, LC
  • Poon, AFY
  • Martin, JN
  • Hatano, H
  • Deeks, SG
  • Harrigan, PR
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3458959?pdf=render
No data is associated with this publication.
Abstract

The evolution of drug resistance mutations in plasma samples is relatively well-characterized. However, the viral population and diversity in other body compartments such as peripheral blood mononuclear cells (PBMC) remains poorly understood. Previous stud

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