High-Throughput Genetic and Gene Expression Analysis of the RNAPII-CTD Reveals Unexpected Connections to SRB10/CDK8
- Author(s): Krogan, Nevan
- Aristizabal, MJ
- Negri, GL
- Benschop, JJ
- Holstege, FCP
- Krogan, NJ
- Kobor, MS
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3757075?pdf=render
The C-terminal domain (CTD) of RNA polymerase II (RNAPII) is composed of heptapeptide repeats, which play a key regulatory role in gene expression. Using genetic interaction, chromatin immunoprecipitation followed by microarrays (ChIP-on-chip) and mRNA exp
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