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Plasma membrane calcium ATPase regulates bone mass by fine-tuning osteoclast differentiation and survival

  • Author(s): Pearce, David
  • Bhargava, Aditi
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3529522?pdf=render
No data is associated with this publication.
Abstract

The precise regulation of Ca2+ dynamics is crucial for proper differentiation and function of osteoclasts. Here we show the involvement of plasma membrane Ca2+ ATPase (PMCA) isoforms 1 and 4 in osteoclastogenesis. In immature/undifferentiated cells, PMCAs

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