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Open Access Publications from the University of California

Predictors of pathologic outcome of focal FDG uptake in the parotid gland identified on whole-body FDG PET imaging

  • Author(s): Mabray, MC
  • Behr, SC
  • Naeger, DM
  • Flavell, RR
  • Glastonbury, CM
  • et al.

© 2015 Elsevier Inc. Purpose: The purpose was to test whether patient's primary malignancy type and presence of F-18-fluorodeoxyglucose (FDG)-avid cervical lymph node(s) are predictors of pathologic outcome of incidental focal FDG-avid parotid lesions. Basic procedures: A retrospective cohort study of pathologically proven incidental cases was performed. Main findings: Focal parotid FDG uptake in the setting of head and neck cancer/melanoma [odds ratio (OR)=24.6, P < .01], lymphoma (OR=7.2, P=.02), or FDG-avid cervical lymph node(s) (OR=3.6, P=.07) has a higher odds of representing metastases. No malignant primary parotid tumors were incidentally discovered. Principal conclusions: In patients with head and neck cancer/melanoma, lymphoma, or FDG-avid cervical lymph node(s), there were higher odds that focal parotid FDG uptake was a metastasis.

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