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Downregulation of MicroRNA-9 in iPSC-Derived Neurons of FTD/ALS Patients with TDP-43 Mutations

  • Author(s): Miller, Bruce
  • Farese, Robert
  • Zhang, Z
  • Almeida, S
  • Lu, Y
  • Nishimura, AL
  • Peng, L
  • Sun, D
  • Wu, B
  • Karydas, AM
  • Tartaglia, MC
  • Fong, JC
  • et al.

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Transactive response DNA-binding protein 43 (TDP-43) is a major pathological protein in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). There are many disease-associated mutations in TDP-43, and several cellular and animal models wit

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