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Ribozymes: structure and mechanism in RNA catalysis.

  • Author(s): Scott, WG;
  • Klug, A
  • et al.
Abstract

The hammerhead RNA is a small catalytic RNA found in a number of RNA virus genomes and virus-like RNAs. The recently determined crystal structures of hammerhead ribozymes reveal how a small RNA motif can fold up into a conformation suitable for mediating RNA cleavage

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