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Open Access Publications from the University of California

Efficacy of a metalloproteinase inhibitor in spinal cord injured dogs

  • Author(s): Werb, Zena
  • Levine, JM
  • Cohen, ND
  • Heller, M
  • Fajt, VR
  • Levine, GJ
  • Kerwin, SC
  • Trivedi, AA
  • Fandel, TM
  • Modestino, A
  • et al.

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Matrix metalloproteinase-9 is elevated within the acutely injured murine spinal cord and blockade of this early proteolytic activity with GM6001, a broad-spectrum matrix metalloproteinase inhibitor, results in improved recovery after spinal cord injury. As

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