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Open Access Publications from the University of California

Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation.

  • Author(s): Verdin, Eric
  • Novis, CL
  • Archin, NM
  • Buzon, MJ
  • Round, JL
  • Lichterfeld, M
  • Margolis, DM
  • Planelles, V
  • Bosque, A
  • et al.

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Toll-like receptors (TLRs) are crucial for recognition of pathogen-associated molecular patterns by cells of the innate immune system. TLRs are present and functional in CD4⁺ T cells. Memory CD4⁺ T cells, predominantly central memory cells (TCM), constitut

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