Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus
- Author(s): Criswell, Lindsey
- McCune, Joseph
- Sacre, K
- Criswell, LA
- McCune, JM
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3446541?pdf=render
Introduction: Plasmacytoid dendritic cells (pDCs) constitutively express two members of the Toll-like receptor (TLR) family, TLR-9 and TLR-7, through which they can be stimulated to produce high levels of interferon (IFN)-α, a key mediator of the pathogene
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