Rifabutin corneal deposits localized to the deep stroma using anterior segment optical coherence tomography.
- Author(s): Zhang, Tianyi
- Sun, Catherine Q
- Lin, Yijie B
- Schallhorn, Julie M
- et al.
Published Web Locationhttps://doi.org/10.1016/j.ajoc.2020.100701
Purpose:To demonstrate that rifabutin-related corneal deposits are localized to the deep stroma using anterior segment optical coherence tomography (OCT) and confocal microscopy. Observations:A 55-year-old male with a history of human immunodeficiency virus (HIV) and disseminated mycobacterium avium complex on rifabutin treatment for 3 years presented with bilateral corneal deposits. Confocal microscopy and anterior segment OCT confirm that rifabutin-related corneal deposits are located in the deep stroma, rather than in the endothelium. Conclusions:And Importance: Rifabutin deposits localize to the deep corneal stroma, and can be seen with both confocal microscopy and anterior segment OCT. Anterior segment OCT is a widely available and easily used diagnostic tool, and can provide utility in the diagnosis of corneal deposits.