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Cytosolic BMAL1 moonlights as a translation factor
Published Web Location
http://www.ncbi.nlm.nih.gov/pubmed/26256246No data is associated with this publication.
Abstract
It is widely recognized that BMAL1 is an essential subunit of the primary transcription factor that drives rhythmic circadian transcription in the nucleus. In a surprising turn, Lipton et al. now show that BMAL1 rhythmically interacts with translational machinery in the cytosol to stimulate protein synthesis in response to mTOR signaling.
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