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Mutational landscape and predictors of survival in head and neck mucosal melanoma.
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https://doi.org/10.1002/alr.23267Abstract
Head and neck mucosal melanomas have a diverse mutational landscape with low mutational burden. A molecular subset (∼13%) has ROS1 mutations, which is an actionable driver mutation. ROS1-mutated patients have improved overall survival likely due to high mutational burden.
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