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Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting

Published Web Location

http://europepmc.org/articles/PMC4862753?pdf=render
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Abstract

© Mavor et al.Ubiquitin is essential for eukaryotic life and varies in only 3 amino acid positions between yeast and humans. However, recent deep sequencing studies indicate that ubiquitin is highly tolerant to single mutations. We hypothesized that this t

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