Molecular Biophys & Integ Bi

eScholarship stats: History by Item for March through June, 2025

Item	Title	Total requests	2025-06	2025-05	2025-04	2025-03
1xt5762k	Improving photosynthesis and crop productivity by accelerating recovery from photoprotection	235	70	66	39	60
6xs6568m	Slot Blot Assay for Detection of R Loops	207	85	67	41	14
0hh6m30h	A Selection for Assembly Reveals That a Single Amino Acid Mutant of the Bacteriophage MS2 Coat Protein Forms a Smaller Virus-like Particle	201	43	120	23	15
3gz3w9v7	Accurate prediction of protein structures and interactions using a three-track neural network	193	87	48	26	32
33c9b7zs	Franck–Condon and Herzberg–Teller Signatures in Molecular Absorption and Emission Spectra	191	48	46	57	40
1tv006vv	XFEL serial crystallography reveals the room temperature structure of methyl-coenzyme M reductase	161	53	51	48	9
1mx9f7xh	Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study	157	47	40	33	37
9wv8c0w6	Operando Unveiling of Hydrogen Spillover Mechanisms on Tungsten Oxide Surfaces	153	33	25	35	60
2ct9j9m4	Real-time bioelectronic sensing of environmental contaminants	148	59	28	23	38
9033s7sx	Novel bacterial clade reveals origin of form I Rubisco	143	56	29	25	33
1r17q430	Oxidation State and Surface Reconstruction of Cu under CO2 Reduction Conditions from In Situ X‑ray Characterization	135	57	28	25	25
08q2m81s	Understanding the Oxygen Evolution Reaction Mechanism on CoO x using Operando Ambient-Pressure X‑ray Photoelectron Spectroscopy	134	53	31	23	27
79v1z4mf	Process Robustness in Lipid Nanoparticle Production: A Comparison of Microfluidic and Turbulent Jet Mixing	132	28	24	16	64
8b29f5c4	Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I	121	32	15	41	33
4z5380qs	Gaussian processes for autonomous data acquisition at large-scale synchrotron and neutron facilities	119	47	26	20	26
4f90v181	Metal–Ligand Cooperativity via Exchange Coupling Promotes Iron- Catalyzed Electrochemical CO2 Reduction at Low Overpotentials	114	36	21	24	33
77j1n0fs	Novel fold of rotavirus glycan-binding domain predicted by AlphaFold2 and determined by X-ray crystallography	112	54	19	18	21
4483825h	Visualizing chaperone-assisted protein folding	111	58	18	15	20
5hv4n8hb	Accurate computational design of three-dimensional protein crystals	109	49	26	15	19
1bf5p8rn	Chlorophyll to zeaxanthin energy transfer in nonphotochemical quenching: An exciton annihilation-free transient absorption study	108	44	31	19	14
5qd5w839	Diagnostic Accuracy of Amyloid versus 18F‐Fluorodeoxyglucose Positron Emission Tomography in Autopsy‐Confirmed Dementia	106	26	64	7	9
94j204sp	Likelihood-based interactive local docking into cryo-EM maps in ChimeraX	105	29	67	4	5
3kh879vk	Quantitative Protein Corona Composition and Dynamics on Carbon Nanotubes in Biological Environments	104	55	21	15	13
4s13w81q	The cryo-electron microscopy structure of human transcription factor IIH	103	66	21	8	8
618496d5	Phycobilisome protein ApcG interacts with PSII and regulates energy transfer in Synechocystis	103	41	32	9	21
6x87029n	Imaging the Progression of Radiolytic Damage in Molecular Crystals with Scanning Nanobeam Electron Diffraction	101	61	40
3x2499cg	Improving Protein Expression, Stability, and Function with ProteinMPNN	100	28	33	27	12
7ct187h2	A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence	100	42	19	13	26
1pb2b52f	Exploring the repeat protein universe through computational protein design	99	55	20	16	8
3rr259j7	CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes	99	51	16	10	22
6g3568w2	Deconstruction of plant biomass by a Cellulomonas strain isolated from an ultra-basic (lignin-stripping) spring	98	47	29	11	11
8mj5k4hc	Reproducibility of protein x-ray diffuse scattering and potential utility for modeling atomic displacement parameters	97	23	67	4	3
4f55w41k	Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix	96	38	35	8	15
4gq0b002	A robust and interpretable machine learning approach using multimodal biological data to predict future pathological tau accumulation	96	39	27	15	15
2qm6f21z	CymA and Exogenous Flavins Improve Extracellular Electron Transfer and Couple It to Cell Growth in Mtr-Expressing Escherichia coli	95	43	20	18	14
5d1456nn	Probing the Surface of Platinum during the Hydrogen Evolution Reaction in Alkaline Electrolyte	94	37	26	9	22
7rh7j0f2	Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48	94	49	25	11	9
6jb5z7bf	Snapshot transient absorption spectroscopy: toward in vivo investigations of nonphotochemical quenching mechanisms	93	38	15	21	19
6nv0q883	De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals	93	35	21	16	21
38v3k44n	Accelerating x‐ray tracing for exascale systems using Kokkos	91	38	9	9	35
7214v1z7	Solvent flows, conformation changes and lattice reordering in a cold protein crystal	91	47	30	10	4
9xb1m8xs	The Role of Cu3+ in the Oxygen Evolution Activity of Copper Oxides	91	91
50p8x432	Omnidirectional Harvesting of Weak Light Using a Graphene Quantum Dot-Modified Organic/Silicon Hybrid Device	90	72	9	7	2
5vf7b95d	Enzyme intermediates captured “on the fly” by mix-and-inject serial crystallography	90	36	40	7	7
41x483dn	The R‐factor gap in macromolecular crystallography: an untapped potential for insights on accurate structures	88	63	12	6	7
9kn3b3xx	ExaFEL: extreme-scale real-time data processing for X-ray free electron laser science	88	20	8	12	48
0zq8m88b	Defying Thermodynamics: Stabilization of Alane Within Covalent Triazine Frameworks for Reversible Hydrogen Storage	87	46	26	9	6
3vt0g6n0	Seeded stimulated X-ray emission at 5.9 keV.	87	60	17	7	3
96r3k4gc	High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States	87	41	19	19	8
30q1m48t	DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors	86	45	21	11	9

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