Open Access Policy Deposits

Parent: Department of Biological Chemistry, UCLA, David Geffen School of Medicine

eScholarship stats: History by Item for March through June, 2025

ItemTitleTotal requests2025-062025-052025-042025-03
3bm6r902Cell Biology of the Mitochondrion17246294453
4h4495x5Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase15912114159
0nj3p8snCell Biology of Canonical Wnt Signaling15356332242
1q76t50gLactate dehydrogenase activity drives hair follicle stem cell activation14812014104
9q72d0dkCRISPR-based targeting of DNA methylation in Arabidopsis thaliana by a bacterial CG-specific DNA methyltransferase14263302425
8cs8z9p3Improving the solubility of pseudo-hydrophobic chemicals through co-crystal formulation.13422274243
68v1446kPhotoaffinity labelling strategies for mapping the small molecule–protein interactome1307140136
9185g8gjHistone H3 lysine 4 methylation recruits DNA demethylases to enforce gene expression in Arabidopsis.13078231514
0fh0h194Double assurance in the induction of axial development by egg dorsal determinants in Xenopus embryos12947282133
4q99m9rwAccurate design of co-assembling multi-component protein nanomaterials1287157
0w64157xInternal Fragments Enhance Middle-Down Mass Spectrometry Structural Characterization of Monoclonal Antibodies and Antibody-Drug Conjugates.12326241657
59b2218pDesign of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces1145460
9nh2d4t3The cardiomyocyte disrupts pyrimidine biosynthesis in non-myocytes to regulate heart repair11443311525
06k5w7g0Structure of the lens MP20 mediated adhesive junction.112433435
77t5d3q4ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.108316737
4ph8w0v1Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing10750212214
3g79735qMicroED Structures of Fluticasone Furoate and Fluticasone Propionate Provide New Insights into Their Function.106413134
5vg8s806Systematic discovery of conservation states for single-nucleotide annotation of the human genome.10425201643
2mc7j5vsTandem metabolic reaction-based sensors unlock in vivo metabolomics.103373135
56j017g9Single nucleus multi-omics identifies human cortical cell regulatory genome diversity10137311716
6274g8m7Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health101365087
05p11699Uncovering the Elusive Structures and Mechanisms of Prevalent Antidepressants.10030101248
8xm482tkEngineering an allosteric transcription factor to respond to new ligands.100731656
5272f4bcA functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience996218811
70b2315vDNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS)9943231419
6qp7s3ccAsparagine promotes cancer cell proliferation through use as an amino acid exchange factor97344797
064987qhRecovering high-resolution information using energy filtering in MicroED.955144
6vq1b3psSpatial profiling of the interplay between cell type- and vision-dependent transcriptomic programs in the visual cortex9536221225
8f18t8wnAtomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.95691178
9bd8z0hhSubstrate twinning activates the signal recognition particle and its receptor9527282218
6cn1q64tDefects in the Medial Entorhinal Cortex and Dentate Gyrus in the Mouse Model of Sanfilippo Syndrome Type B94275296
6nv0q883De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals9335211621
8mx9d13mCLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization9350191311
08d3p8vkAsparagine couples mitochondrial respiration to ATF4 activity and tumor growth9239231515
54g7c1bpCortical regulation of helping behaviour towards others in pain.9230211526
5pr5k9vrEnergy filtering enables macromolecular MicroED data at sub-atomic resolution.92382925
1z72474sBMP gradients: A paradigm for morphogen-mediated developmental patterning9131251421
38v8j6fzA high-resolution map of human evolutionary constraint using 29 mammals9149131712
78z3640xGenome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula9136161722
5v00z3sfAtlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy.904922712
62j4r8dnStructure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression903456
7s9850mtN-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung Carcinoma905023134
82q3d98qVision-dependent specification of cell types and function in the developing cortex9039202011
8619753xIn vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse.9033131727
2b27t47jStructural Characterization of a Thrombin-Aptamer Complex by High Resolution Native Top-Down Mass Spectrometry8979415
3t8708z1Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes8933131726
9nf8q0shHistone H3 cysteine 110 enhances iron metabolism and modulates replicative life span in Saccharomyces cerevisiae.89342926
9nj3h75bTop-down proteomics.894526108
07r1j11rInsight into the autoproteolysis mechanism of the RsgI9 anti-σ factor from Clostridium thermocellum.885614153
35s312ffAn activation-based high throughput screen identifies caspase-10 inhibitors88402424

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