Department of Cellular & Molecular Medicine - Open Access Policy Deposits

eScholarship stats: Breakdown by Item for March through June, 2026

Item	Title	Total requests	Download	View-only	%Dnld
7rs018c6	Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies	774	681	93	88.0%
9wk3d379	Guidelines for the use and interpretation of assays for monitoring autophagy	622	307	315	49.4%
9044v022	Brain organoids, consciousness, ethics and moral status	556	347	209	62.4%
172879gx	Age-Dependent Brain Gene Expression and Copy Number Anomalies in Autism Suggest Distinct Pathological Processes at Young Versus Mature Ages	531	62	469	11.7%
0jb936p7	Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies	470	205	265	43.6%
551458jj	APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia	469	259	210	55.2%
3pv76061	E-cigarettes compromise the gut barrier and trigger inflammation	419	198	221	47.3%
5s47j042	First Organoid Intelligence (OI) workshop to form an OI community	410	206	204	50.2%
0914g67c	A comparative atlas of single-cell chromatin accessibility in the human brain	395	240	155	60.8%
00g3j9wp	Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer’s disease	392	239	153	61.0%
70c3m48j	Spindle assembly checkpoint activation and silencing at kinetochores	377	207	170	54.9%
28k88901	Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content	366	252	114	68.9%
3cv2t1d1	Mechanism and reconstitution of circadian transcription in cyanobacteria	356	203	153	57.0%
4bd0d5ws	An environment-dependent transcriptional network specifies human microglia identity	346	186	160	53.8%
2nz1949j	A large-scale binding and functional map of human RNA-binding proteins	343	232	111	67.6%
0r30n2q3	Adipose tissue macrophages secrete small extracellular vesicles that mediate rosiglitazone-induced insulin sensitization	339	193	146	56.9%
1jm982xv	Decoding ALS: from genes to mechanism	339	182	157	53.7%
10h0243m	Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection	332	190	142	57.2%
8fz9q8fw	Lipid-associated macrophages’ promotion of fibrosis resolution during MASH regression requires TREM2	329	238	91	72.3%
2pp4w8dz	The complexity of tobacco smoke-induced mutagenesis in head and neck cancer	327	191	136	58.4%
3mk2678t	Exploring the consequences of redirecting an exocytic Rab onto endocytic vesicles	318	253	65	79.6%
2bq0m1f2	Reduced signal for polygenic adaptation of height in UK Biobank	298	162	136	54.4%
68k9w7dj	A living organoid biobank of patients with Crohn’s disease reveals molecular subtypes for personalized therapeutics	291	209	82	71.8%
1m706149	Reversing a model of Parkinson’s disease with in situ converted nigral neurons	288	189	99	65.6%
4vt1n111	A phage nucleus-associated RNA-binding protein is required for jumbo phage infection	284	102	182	35.9%
4ch9n51h	Mitotic tethering enables inheritance of shattered micronuclear chromosomes	280	146	134	52.1%
0503r9x1	Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19	275	182	93	66.2%
7m89k316	Nuclear miR-320 Mediates Diabetes-Induced Cardiac Dysfunction by Activating Transcription of Fatty Acid Metabolic Genes to Cause Lipotoxicity in the Heart	274	187	87	68.2%
0063305k	Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells	270	67	203	24.8%
16h8932r	Multiomic QTL mapping reveals phenotypic complexity of GWAS loci and prioritizes putative causal variants	268	116	152	43.3%
6nt244k4	Generation of ‘semi-guided’ cortical organoids with complex neural oscillations	267	156	111	58.4%
9jp3g347	The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein	262	118	144	45.0%
01j548f4	Perspectives on ENCODE	260	165	95	63.5%
0bw638xs	Architecture and self-assembly of the jumbo bacteriophage nuclear shell	260	120	140	46.2%
8vw4s1s8	Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)	257	96	161	37.4%
60k166zd	The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1	251	54	197	21.5%
0tt0x846	Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management	248	121	127	48.8%
1k65z54f	Microbiome–microglia connections via the gut–brain axis	248	138	110	55.6%
2gr9g49c	Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity	243	72	171	29.6%
6z9096mf	An in vivo neuroimmune organoid model to study human microglia phenotypes	242	105	137	43.4%
8670n4cq	Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions	240	102	138	42.5%
0xm8q84f	Circular ecDNA promotes accessible chromatin and high oncogene expression	237	62	175	26.2%
3pd6q5r4	Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation	237	82	155	34.6%
8bg9p9r4	Messenger RNA Oxidation Occurs Early in Disease Pathogenesis and Promotes Motor Neuron Degeneration in ALS	237	136	101	57.4%
9093x51q	Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development	237	77	160	32.5%
27v4m3md	Role of H3K4 monomethylation in gene regulation	236	81	155	34.3%
4vs4p782	Endosomal escape of RNA therapeutics: How do we solve this rate-limiting problem?	236	109	127	46.2%
8f133727	SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism	235	61	174	26.0%
20t6f25j	Rebuilding Chromosomes After Catastrophe: Emerging Mechanisms of Chromothripsis	232	67	165	28.9%
13v7056h	Identification of the bacteriophage nucleus protein interaction network	231	81	150	35.1%

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