Biological Systems & Engineering

eScholarship stats: History by Item for July through October, 2026

Item	Title	Total requests	2026-10	2026-09	2026-08	2026-07
4j8893w1	Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging	1,630	127	578	820	105
60s4z9wm	Tumour exosome integrins determine organotropic metastasis	938	287	203	331	117
2n42n48w	The Impact of Electric Fields on Processes at Electrode Interfaces	866	333	230	151	152
9d4221mc	De novo DNA synthesis using polymerase-nucleotide conjugates	748	220	168	139	221
5n75t404	Pre-metastatic niches: organ-specific homes for metastases	653	140	136	202	175
1gq1w12k	Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype	631	252	132	176	71
1dg2k0bw	Functionalized benzylamines from commercial kraft lignin	617	502	48	29	38
3799153s	33 Unresolved Questions in Nanoscience and Nanotechnology	612	195	133	258	26
2mq4z3j6	Complete biosynthesis of QS-21 in engineered yeast	610	163	118	192	137
77f5s184	The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice	579	128	192	220	39
9pm0x5mh	Machine learning for metabolic engineering: A review	569	161	93	144	171
2z5184j0	Comparing in planta accumulation with microbial routes to set targets for a cost-competitive bioeconomy	567	496	22	36	13
2zw971kg	Metabolic engineering strategies for sesquiterpene production in microorganism	518	169	106	168	75
6xs6568m	Slot Blot Assay for Detection of R Loops	495	88	58	180	169
3939k3wv	Land Resources for Wind Energy Development Requires Regionalized Characterizations	475	141	98	151	85
5k4761zn	A comparative study of ethanol production using dilute acid, ionic liquid and AFEX™ pretreated corn stover	439	338	46	25	30
6bz273tk	Galactic cosmic ray simulation at the NASA space radiation laboratory – Progress, challenges and recommendations on mixed-field effects	435	172	99	82	82
7s7342wx	Evaluation of bacterial hosts for conversion of lignin-derived p-coumaric acid to 4-vinylphenol	431	107	90	109	125
75g874b4	Biosystem design of Corynebacterium glutamicum for bioproduction	422	163	80	102	77
6940v666	Prospective Study Reveals Host Microbial Determinants of Clinical Response to Fecal Microbiota Transplant Therapy in Type 2 Diabetes Patients	414	157	65	84	108
6r99w1b4	Complete biosynthesis of cannabinoids and their unnatural analogues in yeast	408	112	103	110	83
2jx454ms	Neurospora intermedia from a traditional fermented food enables waste-to-food conversion	392	150	93	74	75
5ns091ht	Atacama Large Aperture Submillimeter Telescope (AtLAST) science: Resolving the hot and ionized Universe through the Sunyaev-Zeldovich effect	391	112	72	87	120
7294g81k	Heterochromatin: Guardian of the Genome	386	121	61	103	101
25s902m0	Microbial production of advanced biofuels	382	147	64	81	90
2ww6f9d2	Complete genomic and epigenetic maps of human centromeres	381	92	98	113	78
1t0500f3	Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition	379	143	108	64	64
2nx9f1fj	Thirdhand Smoke: New Evidence, Challenges, and Future Directions	374	157	75	70	72
46b3v6xc	Geroscience: Linking Aging to Chronic Disease	372	88	76	130	78
71q1b4jn	A map of the rubisco biochemical landscape	371	116	96	84	75
1ct062cx	Nitrogen Metabolism in Pseudomonas putida: Functional Analysis Using Random Barcode Transposon Sequencing	363	165	58	67	73
2409f20f	Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus	362	147	99	70	46
5km8x4kd	Investigation of Indigoidine Synthetase Reveals a Conserved Active-Site Base Residue of Nonribosomal Peptide Synthetase Oxidases	360	168	67	50	75
6q23g280	A proteomic atlas of senescence-associated secretomes for aging biomarker development	358	171	47	81	59
61r4c30v	Deconstruction of Woody Biomass via Protic and Aprotic Ionic Liquid Pretreatment for Ethanol Production	355	179	55	55	66
7cx5710p	1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life	354	173	53	47	81
3qf33012	Binary vector copy number engineering improves Agrobacterium-mediated transformation	351	93	73	97	88
13p8z1db	Techno-economic analysis and life-cycle greenhouse gas mitigation cost of five routes to bio-jet fuel blendstocks	349	160	76	73	40
2zr0520r	Advanced pathways for hydrogen production: a collective view from a technical experts meeting	345	56	142	123	24
0x93g6g7	Building a global alliance of biofoundries	343	146	53	80	64
6dr6v4vg	Adsorptive recovery of volatile fatty acids from wastewater fermentation broth	343	132	95	76	40
8xg3g0x6	IMG/PR: a database of plasmids from genomes and metagenomes with rich annotations and metadata	342	162	57	53	70
37n249x2	Engineering Robust Production Microbes for Large-Scale Cultivation	336	173	63	50	50
9fm771xp	Genomic Encyclopedia of Bacteria and Archaea: Sequencing a Myriad of Type Strains	329	158	46	58	67
06n5h0nh	Hydrogen storage and geo-methanation in a depleted underground hydrocarbon reservoir	320	141	55	77	47
80x495z8	Cooperative Brønsted-Lewis acid sites created by phosphotungstic acid encapsulated metal–organic frameworks for selective glucose conversion to 5-hydroxymethylfurfural	318	147	61	48	62
2hg7004n	Systematic assessment of long-read RNA-seq methods for transcript identification and quantification	315	104	36	66	109
3bq8277b	Edible mycelium bioengineered for enhanced nutritional value and sensory appeal using a modular synthetic biology toolkit	307	112	58	76	61
6kk0p32c	ARDD 2020: from aging mechanisms to interventions	307	139	53	38	77
7wc0h0qq	Machine learning for surrogate process models of bioproduction pathways	306	132	70	49	55

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